Distinct DNA methylation signature found in the cord blood of newborns...
A new study led by UC Davis MIND Institute researchers found a distinct DNA methylation signature in the cord blood of newborns who were eventually diagnosed with autism spectrum disorder (ASD).
View ArticleNovel insights open up new avenues for treating autoimmune conditions
Immune response is a balancing act: Too much can lead to inflammatory or autoimmune disease; too little could lead to a serious infection. Regulatory T cells, or Tregs, are important players in...
View ArticleConvalescent plasma in COVID-19 can be effective, especially early in disease
A team of researchers in the United States have conducted an extensive literature review looking at the usage of convalescent plasma from recovered COVID-19 patients to treat those with an impaired...
View ArticleStudy reveals molecular machinery that regulates membrane association of Arf...
The small GTPases of the ADP-ribosylation factor (Arf) family are key initiators of various physiological processes including secretion, endocytosis, phagocytosis, and signal transduction. Arf family...
View ArticleCanadian pilot study uses gene therapy to successfully treat patients with...
Results of a world-first Canadian pilot study on patients treated with gene therapy for Fabry disease show that the treatment is working and safe.
View ArticleMGH researchers uncover new clues about X chromosome inactivation
Researchers at Massachusetts General Hospital have uncovered new clues that add to the growing understanding of how female mammals, including humans, "silence" one X chromosome.
View ArticleUVA researcher developing innovative gene therapy to help children with Rett...
A University of Virginia School of Medicine scientist is developing an innovative gene therapy she hopes will slow disease progression and improve movement, coordination and communication in children...
View ArticleFinding ways to reverse a genetic cause of poor stress responses in mice
Everyone faces stress occasionally, whether in school, at work, or during a global pandemic. However, some cannot cope as well as others.
View ArticleCalcified Tissue International announces top 10 most impactful papers of 2019
Calcified Tissue International and Musculoskeletal Research is among the leading peer-reviewed journals publishing original preclinical, translational, and clinical research as well as expert reviews...
View ArticleNew gene-delivering workhorse could make gene therapy safer, more effective...
Genetic muscle diseases lead to progressive muscle wasting and often early death, with few treatment options and no cure.
View ArticleReview of COVID-19 clinical and viral characteristics, pathogenesis, and...
A new review article investigates the clinical and viral characteristics, pathogenesis, as well as human genetic basis associated with COVID-19.
View ArticleFamous scientist joins NYU Langone’s Division of Rheumatology
Nationally recognized for his work studying a novel inflammatory disorder known as VEXAS, David B. Beck, MD, PhD, has joined the Division of Rheumatology at NYU Langone.
View ArticleScientists discover a division of labor between genetic switches
Two X chromosomes are actually one too many. Female mammalian cells hence switch off one of them – but only when the cells start to specialize into tissues.
View ArticleUnderstanding immune responses to SARS-CoV-2 infections in children
A study published in the journal Immunity analyzed the varied manifestations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in children.
View ArticleSurprising discovery about genetic form of microcephaly has potential to...
Virginia Tech researchers publishing in the Journal of Medical Genetics made a discovery about a genetic form of microcephaly -- a condition where babies' heads and brains are smaller and grow more...
View ArticleResearch reveals why a common genetic variant worsens outcomes for people...
A pioneering new study led by UCL and National Institutes of Health (NIH) scientists has revealed, for the first time, why a common genetic variant worsens disease outcomes for people with the...
View ArticleResearchers secure $12 million grant to develop improved therapies for...
An Indiana University School of Medicine researcher will lead a multi-institute effort toward improved therapies for hemophilia with help from a $12 million grant from the National Heart Lung and Blood...
View ArticleStudy takes a new approach to looking at de novo genetic variants in autism
About 1 in 44 children in the U.S. are diagnosed with autism spectrum disorder (ASD) by the age of 8, according to the 2018 Centers for Disease Control and Prevention surveillance. How a child's DNA...
View ArticleKey protein could be a novel target for treatment of patients with B cell...
The rules to the kids' game "red light, green light" are easy to follow: red always means stop, and green always means go. But now, researchers from Japan have found that a key protein involved in B...
View ArticleDo androgens play a role in COVID-19 severity?
Researchers assess the association between the AR polyQ polymorphism with COVID-19 severity using a large cohort of 1,136 COVID-19 male patients.
View Article